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Cat. No. | Product Name | Target | Signaling Pathways |
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T35955 |
PAR2 (1-6) amide (human) (trifluoroacetate salt)
PAR2 (1-6) amide (human) (trifluoroacetate salt) |
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PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod... | |||
T36717 |
RWJ-56110 dihydrochloride
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RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 . RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell ap... |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01031 |
CAPN2 Protein, Human, Recombinant (His)
Calpain-2 catalytic subunit,Millimolar-calpain,Calpain-2 lar... |
Human | E. coli |
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82... | |||
TMPJ-01448 |
3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His)
M Proteinase,3CL Proteinase |
2019-nCoV | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant (His) is expressed in E. coli expression system with N-6xHis t... | |||
TMPJ-01449 |
3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant
M Proteinase,3C-like Proteinase,3CL Pr... |
SARS-CoV-2 | E. coli |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molec... | |||
TMPK-01346 |
3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant
3CL-Mpro,Mpro,M Proteinase,3CL Protease |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8kDa and the accession number is YP_009725301.1. | |||
TMPK-01339 |
3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant
3CL-Mpro,M Proteinase,3CL Protease,Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.78 kDa and the accession number is YP_009725301.1. | |||
TMPK-01336 |
3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant
3CL-Mpro,3CL Protease,M Proteinase,Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1. | |||
TMPK-01335 |
3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant
M Proteinase,Mpro,3CL Protease,3CL-Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1. | |||
TMPK-01343 |
3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant
3CL-Mpro,M Proteinase,Mpro,3CL Protease |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1. | |||
TMPK-01344 |
3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant
M Proteinase,Mpro,3CL-Mpro,3CL Protease |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5kDa and the accession number is YP_009725301.1. | |||
TMPK-01342 |
3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant
Mpro,3CL-Mpro,3CL Protease,M Proteinase |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.8kDa and the accession number is YP_009725301.1. | |||
TMPK-01347 |
3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant
3CL-Mpro,3CL Protease,M Proteinase,Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.4kDa and the accession number is YP_009725301.1. | |||
TMPK-01337 |
3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant
Mpro,3CL-Mpro,3CL Protease,M Proteinase |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.79 kDa and the accession number is YP_009725301.1. | |||
TMPK-01341 |
3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant
3CL Protease,3CL-Mpro,Mpro,M Proteinase |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1. | |||
TMPK-01345 |
3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant
3CL-Mpro,Mpro,M Proteinase,3CL Protease |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5 kDa and the accession number is YP_009725301.1. | |||
TMPK-01338 |
3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant
M Proteinase,3CL-Mpro,Mpro,3CL Protease |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.82 kDa and the accession number is YP_009725301.1. | |||
TMPK-01340 |
3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant
3CL-Mpro,3CL Protease,M Proteinase,Mpro |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.72 kDa and the accession number is YP_009725301.1. | |||
TMPK-01348 |
3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)
COVID-19,3CL Protease,M Proteinase,3CL Pro,3CL-Mpro... |
SARS-CoV-2 | E. coli |
3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1. |